A case-study of the interaction between philosophical context and observational data in the practice of Science.

This study examines how low-income African American mothers of children with sickle cell disease cope with the reproductive implications of having passed a genetic disease on to their children. Based on in-depth interviews with 29 African American mothers, I found that most mothers knew about SCD prior to having a child with the disease; many knew they were carriers of the sickle cell trait. In explaining why this knowledge did not lead them to alter their reproductive behaviors, mothers invoked a (...) theme of medical mismanagement; that is, they said the genetic screening programs for SCD did not provide them with enough medical knowledge about the disease. The implication that adequate knowledge about SCD would have affected their childbearing choices, however, is contradicted by their subsequent reproductive behaviors. I argue that the SCD diagnosis threatened motherhood, an important cultural value among low-income African American women, and that they protected their reproductive autonomy by obfuscating SCD medical knowledge. (shrink)

During the eighteenth century, the specter of atheism was a major concern among many intellectuals in Europe. Many of the leading figures of the period such as François-Marie Arouet de Voltaire refuted atheism at every turn. These debates centered on living organisms, particularly questions about generation. Efforts to explain the process of generation raised biological, religious, and political questions. One popular theory put forward to address the question of generation was preformation, the belief that “germs” had been in existence since (...) God created the world. This chapter first discusses the rise of preformationist thinking in the late seventeenth century before turning to the biological evidence that challenged preexistence in the mid-eighteenth century and analyzing the reaction it triggered among the preformationists. It also examines the work of Voltaire and Denis Diderot to illustrate how the generation debates are linked to the materialism question. The chapter concludes by showing how these controversies about nature and biology became entangled with politics in eighteenth-century France. (shrink)

This book presents the psychological basis, methodology, and application of Marton's phenomenographic approach to the theory of learning.

Managers often encounter situations that require them to make decisions with ethical implications that affect the organization as well as the managers themselves. The issue we address in this study concerns whether the ethical consistency of managerial decisions is situation dependent. That is, are the decisions managers make ethically consistent when they are faced with different ethical situations? We hypothesize that managerial decisions will vary depending on the type of ethical situation they encounter. We also hypothesize that gender plays a (...) role in determining the ethical consistency of managerial decisions. Results of statistical analyses support our hypotheses. (shrink)

Within the context of employee rights and management social responsibility, this paper identifies and explores three ethical dimensions of downsizing. Using ANOVA and Scheffe post-hoc statistical techniques, groups involved in the downsizing decision making process were compared with groups affected by the process on each ethical dimension. Results indicated that those affected by the process attached greater ethical significance to these dimensions than those who were involved in formulating and implementing/communicating downsizing decisions.

It is widely believed that gendered expectations are communicated to children in the process of socialization. However, there is reason to ask whether and how gender is constructed in Black families. An early perspective that still continues to inform some contemporary research is assimilationism, which assumes that Black people embrace and pass on to their children the gender norms of the dominant white society. The Afrocentric perspective challenges this view, maintaining that the unique historical experiences of Blacks have militated against (...) an emphasis on rigid gender distinctions, and that relative gender neutrality exists in Black families' child-rearing practices. The development of multicultural feminist theory, which argues that the impact of race on gender varies by social class, implies that both assimilationism and Afrocentrism may be overgeneralizations. Yet, little systematic research has been done on whether race makes a difference in how parents view gender. The authors use data from surveys completed by a nonrandom sample of parents in 202 African American and 204 white families in two large metropolitan school districts to examine the impact of gender, race, and class on parents' self-reports of their immediate priorities and long-term goals for their children, their view of the parenting role, and their discipline strategies. The findings are consistent with multicultural feminist theory: Race and social class interact to shape the intergenerational construction of gender in families. (shrink)

Aggleton & Brown argue that a hippocampal-anterior thalamic system supports the “recollection” of contextual information about previous events, and that a separate perirhinal-medial dorsal thalamic system supports detection of stimulus “familiarity.” Although there is a growing body of human literature that is in agreement with these claims, when recollection and familiarity have been examined in amnesics using the process dissociation or the remember/know procedures, the results do not seem to provide consistent support. We reexamine these studies and describe the results (...) of an additional experiment using a receiver operating characteristic (ROC) technique. The results of the reanalysis and the ROC experiment are consistent with Aggleton & Brown's proposal. Patients with damage to both regions exhibit severe deficits in recollection and smaller, but consistent, deficits in familiarity. (shrink)

The Oxford University Studies in the Enlightenment series, previously known as SVEC (Studies on Voltaire and the Eighteenth Century), has published over 500 peer-reviewed scholarly volumes since 1955 as part of the Voltaire Foundation at the University of Oxford. International in focus, Oxford University Studies in the Enlightenment volumes cover wide-ranging aspects of the eighteenth century and the Enlightenment, from gender studies to political theory, and from economics to visual arts and music, and are published in English or French.

The stereotyped pattern of cell commitments during leech embryogenesis is described. The nature of cell commitments during segmentation differs significantly between leech and fruit fly. Despite the constancy of cell fate assignments in normal development, ablation experiments show that cell interactions are essential in setting some of these commitments. Interacting cells follow a positionally determined hierarchy of fate choices. For other cells, which appear to have fates fixed from birth, the possibility of determinative interactions between mother and daughter cells is (...) discussed. (shrink)

Samuel Shirley's splendid new translation, with critical annotation reflecting research of the last half-century, is the only edition of the complete text of Spinoza's correspondence available in English. An historical-philosophical Introduction, detailed annotation, a chronology, and a bibliography are also included.

According to John Macmurray, action is the starting-point for an analysis of persons, who exist only in relation. This paper re-examines Macmurray’s argument from action and finds it lacking. However, rather than implying an obstacle to a relational definition of persons, the failure to arrive at this definition provides the opening or space wherein God, who is fully relational, can be revealed. The implications for human persons are mirrored in the dual concept of the person found in a social trinitarianism, (...) which lends support to an unexpected affirmation. Persons are found within community, but only by granting priority to the individual does this relational unity, which is the unity of the person, spring to life. (shrink)

Neurosurgery for psychiatric disorders, also sometimes referred to as psychosurgery, is rapidly evolving, with new techniques and indications being investigated actively. Many within the field have suggested that some form of guidelines or regulations are needed to help ensure that a promising field develops safely. Multiple countries have enacted specific laws regulating NPD. This article reviews NPD-specific laws drawn from North and South America, Asia and Europe, in order to identify the typical form and contents of these laws and to (...) set the groundwork for the design of an optimal regulation for the field. Key challenges for this design that are revealed by the review are how to define the scope of the law, what types of regulations are required, and how to approach international harmonization given the potential migration of researchers and patients. (shrink)